免疫原
The antiserum was produced against synthesized peptide derived from human BRP44L. AA range:11-60
特异性
Brp44L Polyclonal Antibody detects endogenous levels of Brp44L protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
The protein encoded by this gene is part of an MPC1/MPC2 heterodimer that is responsible for transporting pyruvate into mitochondria. The encoded protein is found in the inner mitochondrial membrane. Defects in this gene are a cause of mitochondrial pyruvate carrier deficiency. Several transcript variants, some protein coding and one non-protein coding, have been found for this gene. [provided by RefSeq, Aug 2012],
功能
similarity:Belongs to the UPF0041 (0-44) family.,
蛋白名称
Mitochondrial pyruvate carrier 1
其他名称
MPC1; BRP44L; CGI-129; HSPC040; PNAS-115; Mitochondrial pyruvate carrier 1; Brain protein 44-like protein
Fields
>>Diabetic cardiomyopathy
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .
组织表达
Placenta,Promyelocytic leukemia,Skeletal muscle,Umbilical cord blood,