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Msi2 Monoclonal Antibody

说明书

BYab-01005

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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产品简介>

宿主
反应性
应用
WB;IHC;IF;ELISA
分子量(DA)
免疫原
Purified recombinant fragment of human Msi2 expressed in E. Coli.
特异性
Msi2 Monoclonal Antibody detects endogenous levels of Msi2 protein.
来源
Monoclonal, Mouse
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. ELISA: 1/10000.. IF 1:50-200
纯化工艺(Immunogen)
Affinity purification
浓度
背景(Background)
This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016],
功能
disease:Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).,function:RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system.,induction:Up-regulated in astrocytes after brain injury.,PTM:Phosphorylated.,similarity:Belongs to the Musashi family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subcellular location:Associated with polysomes.,tissue specificity:Ubiquitous; detected at low levels.,
基因名称(Gene Name)
MSI2
蛋白名称
RNA-binding protein Musashi homolog 2
简称
Msi2
其他名称
MSI2; RNA-binding protein Musashi homolog 2; Musashi-2
Fields
>>mRNA surveillance pathway
人基因ID
124540
人蛋白质序列数据库
Q96DH6
小鼠基因ID
小鼠蛋白质序列数据库
Q920Q6
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Cytoplasm. Associated with polysomes. .
组织表达
Ubiquitous; detected at low levels.
储存(Storage)
-20°C/1 year

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Msi2 Monoclonal Antibody

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