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GATA-3 Monoclonal Antibody

说明书

BYab-00986

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  • 货期: 3天左右

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产品简介>

宿主
反应性
应用
WB;IHC;IF;ELISA
分子量(DA)
免疫原
Purified recombinant fragment of human GATA-3 expressed in E. Coli.
特异性
GATA-3 Monoclonal Antibody detects endogenous levels of GATA-3 protein.
来源
Monoclonal, Mouse
组成(Formulation)
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. ELISA: 1/10000.. IF 1:50-200
纯化工艺(Immunogen)
Affinity purification
浓度
背景(Background)
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009],
功能
disease:Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.,function:Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:T-cells and endothelial cells.,
基因名称(Gene Name)
GATA3
蛋白名称
Trans-acting T-cell-specific transcription factor GATA-3
简称
GATA-3
其他名称
GATA3; Trans-acting T-cell-specific transcription factor GATA-3; GATA-binding factor 3
Fields
>>Th1 and Th2 cell differentiation;>>Th17 cell differentiation;>>Parathyroid hormone synthesis, secretion and action;>>Inflammatory bowel disease
人基因ID
2624
人蛋白质序列数据库
P23771
小鼠基因ID
小鼠蛋白质序列数据库
P23772
大鼠基因ID
大鼠蛋白质序列数据库
细胞定位
Nucleus.
组织表达
T-cells and endothelial cells.
储存(Storage)
-20°C/1 year

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GATA-3 Monoclonal Antibody

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