免疫原
Synthesized peptide derived from human c-Myb (Acetyl Lys480)
特异性
This antibody detects endogenous levels of Human,Mouse c-Myb (Acetyl Lys480)
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
domain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,
功能
transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
蛋白名称
c-Myb (Acetyl Lys480)
其他名称
Transcriptional activator Myb (Proto-oncogene c-Myb)
Fields
>>PI3K-Akt signaling pathway
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