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v-SNARE Vti1a Polyclonal Antibody

说明书

BYab-00755

  • 20UL ¥460 50UL ¥945 100UL ¥1350
  • 货期: 3天左右

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宿主
反应性
应用
WB;ELISA
分子量(DA)
23kD
免疫原
The antiserum was produced against synthesized peptide derived from human VTI1A. AA range:31-80
特异性
v-SNARE Vti1a Polyclonal Antibody detects endogenous levels of v-SNARE Vti1a protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度
1 mg/ml
背景(Background)
The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
功能
function:V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.,similarity:Belongs to the VTI1 family.,
基因名称(Gene Name)
VTI1A
蛋白名称
Vesicle transport through interaction with t-SNAREs homolog 1A
简称
v-SNARE Vti1a
其他名称
VTI1A; Vesicle transport through interaction with t-SNAREs homolog 1A; Vesicle transport v-SNARE protein Vti1-like 2; Vti1-rp2
Fields
>>SNARE interactions in vesicular transport
人基因ID
143187
人蛋白质序列数据库
Q96AJ9
小鼠基因ID
53611
小鼠蛋白质序列数据库
O89116
大鼠基因ID
65277
大鼠蛋白质序列数据库
Q9JI51
细胞定位
Cytoplasmic vesicle . Golgi apparatus membrane ; Single-pass type IV membrane protein .
组织表达
Lung,
储存(Storage)
-20°C/1 year

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v-SNARE Vti1a Polyclonal Antibody

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