免疫原
The antiserum was produced against synthesized peptide derived from human RAD54B. AA range:241-290
特异性
Rad54B Polyclonal Antibody detects endogenous levels of Rad54B protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The RAD54 homolog B encoded by RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
功能
M phase, double-strand break repair via homologous recombination, recombinational repair, DNA metabolic process,DNA repair, double-strand break repair, DNA recombination, mitotic recombination, response to DNA damage stimulus,cell cycle, meiosis, meiosis I, reciprocal meiotic recombination, response to radiation, response to abiotic stimulus,response to ionizing radiation, cell cycle process, cell cycle phase, cellular response to stress, response to drug,regulation of transcription, meiotic cell cycle, M phase of meiotic cell cycle,
蛋白名称
DNA repair and recombination protein RAD54B
其他名称
RAD54B; DNA repair and recombination protein RAD54B; RAD54 homolog B
Fields
>>Homologous recombination
组织表达
Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon.
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