免疫原
The antiserum was produced against synthesized peptide derived from human TMEPA. AA range:101-150
特异性
PMEPA1 Polyclonal Antibody detects endogenous levels of PMEPA1 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
功能
domain:The WW-binding motifs mediate interaction with NEDD4.,induction:By androgen.,similarity:Belongs to the PMEPA1 family.,subunit:Interacts with the WW domains of NEDD4.,tissue specificity:Highest expression in prostate. Also expressed in ovary.,
蛋白名称
Transmembrane prostate androgen-induced protein
其他名称
PMEPA1; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Solid tumor-associated 1 protein
细胞定位
Early endosome membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.
组织表达
Highest expression in prostate. Also expressed in ovary.
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