免疫原
The antiserum was produced against synthesized peptide derived from human DMC1. AA range:61-110
特异性
Dmc1 Polyclonal Antibody detects endogenous levels of Dmc1 protein.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
DNA meiotic recombinase 1(DMC1) Homo sapiens This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
功能
function:May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.,similarity:Belongs to the recA family. DMC1 subfamily.,similarity:Contains 1 HhH domain.,subunit:Interacts with the MND1-PSMC3IP heterodimer (By similarity). Double stacked ring-shaped homooctamer.,
蛋白名称
Meiotic recombination protein DMC1/LIM15 homolog
其他名称
DMC1; DMC1H; LIM15; Meiotic recombination protein DMC1/LIM15 homolog
细胞定位
Nucleus . Chromosome .
组织表达
Ovary,Testis,Thymus,
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