免疫原
The antiserum was produced against synthesized peptide derived from human TOB1 around the phosphorylation site of Ser164. AA range:130-179
特异性
Phospho-TOB1 (S164) Polyclonal Antibody detects endogenous levels of TOB1 protein only when phosphorylated at S164.
来源
Polyclonal, Rabbit,IgG
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],
功能
function:Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors.,PTM:Phosphorylated on Ser and Thr residues.,similarity:Belongs to the BTG family.,subunit:Interacts with CNOT7.,tissue specificity:Ubiquitous.,
其他名称
TOB1; TOB; TROB1; Protein Tob1; Transducer of erbB-2 1
细胞定位
Cytoplasm . Nucleus . Only a small fraction localizes to the cytoplasm except in late S-phase where more than half of proteins become cytoplasmic. .
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